@article{ajphr2015352,
author={{Esakova, Natalia Vladislavovna and Treneva, Marina Sergeevna and Okuneva, Tatyana Sergeevna and Pampura, Alexander Nikolaevich},
title={Food Anaphylaxis: Reported Cases in Russian Federation Children},
journal={American Journal of Public Health Research},
volume={3},
number={5},
pages={187--191},
year={2015},
url={http://pubs.sciepub.com/ajphr/3/5/2},
issn={2327-6703},
abstract={<b>Background</b><b>:</b> Anaphylaxis is a potentially fatal allergic reaction. Food allergy is one of the main causes of anaphylaxis in children. Anaphylaxis research in different populations across Europe<b> </b>is one of<b> </b>the unmet needs<b>. </b>The aim of this study is to evaluate typical clinical features, causes of food anaphylaxis and sensitization to food allergens in Russian Federation children admitted to the allergy department. <b>Materials and methods</b><b>: </b>Allergy history of<b> </b>80 children with food anaphylaxis was investigated and specific IgE concentration in serum was tested. <b>Results: </b>Total number of anaphylaxis episodes in 80 children was 158. Family allergy history was positive in 42 children. Food anaphylaxis episodes were associated more often with cow milk, fish or/and seafood, tree nuts. Cow milk was reliably more valid in children under 2 years of age than in older children, where tree nut and fruit anaphylaxis was more frequent. Specific IgE levels ¡Ý 0,35 §ÜUA/l to food associated with anaphylaxis episodes were revealed in all children and varied largely. Specific IgE levels did not correlate with severity of anaphylaxis episodes.Clinical manifestations with skin/mucosa and respiratory system involvement were the most frequent (97,5% and 92% respectively). Cardiovascular and gastrointestinal systems were involved in 33,5% of cases each. <b>Conclusion</b><b>: </b>Cow milk, fish and/or seafood, tree nuts are the most often food associated with food anaphylaxis cases in Russian Federation children. Food triggers of anaphylaxis vary with age of children. Skin/mucosa and respiratory tract are often involved in food anaphylaxis episodes. Cardiovascular involvement increases with children¡¯s age.},
doi={10.12691/ajphr-3-5-2}
publisher={Science and Education Publishing}
}