eng Science and Education Publishing American Journal of Nursing Research 2378-5586 2020-10-23 8 6 608 623 10.12691/ajnr-8-6-4 AJNR2020864 article Azza Fathi Ibrahim Mohammed azza_fathy2008@yahoo.com 1 Thoraya Mohammed Abdel Aziz 2 Ola Ezzat Eltohamy 3 Nursing Education Department, Faculty of Nursing, Alexandria University, Egypt Medical-Surgical Nursing Department, Faculty of Nursing, Alexandria University, Egypt Gerontology Nursing Department, Faculty of Nursing, Damanhur University, Egypt Chronic Kidney Disease (CKD) mortality has increased in Egypt; consequently, comprehensive health education is necessitated. This study aimed to: develop and employ, then, evaluate the developed zone tool as a health education strategy on CKD patients¡¯ self-care management and self-efficacy levels. A methodological design was implemented. Two hundred patients with CKD were randomly assigned as an assessment group, then, by systematic random sampling; 30% of them, were recruited as an experimental group. Three tools were used for data collection: Tool one: Patient's sociodemographic and clinical characteristics questionnaire, Tool two: CKD Self-Management Instrument, and Tool three: Self-Efficacy for Managing Chronic Disease Six-Item Scale. Results for the assessment group showed an obvious low level in self-care management and self-efficacy perceptions. After using the developed zone tool among the experimental group; the findings revealed little improvement in clinical characteristic¡¯s values, and considerable improvement in self-care management and self-efficacy perception levels within 1st, 2nd, to 3rd assessments. Conclusion: the developed zone tool is a crucial educational approach to improve CKD patient¡¯s self-care management, and self-efficacy perception levels. Recommendations and further studies: interdisciplinary involvement should be integrated into developing comprehensive and valid CKD health education materials. Evaluation of health education¡¯ compliance among CKD patients is a required study. http://pubs.sciepub.com/ajnr/8/6/4/ajnr-8-6-4.pdf Chronic Kidney disease (CKD) Health education tools Patient's self-care management and Self-efficacy