eng Science and Education Publishing American Journal of Nursing Research 2378-5586 2020-08-30 8 5 575 576 10.12691/ajnr-8-5-10 AJNR20208510 article Nashi Masnad Alreshidi nmalreshidi@moh.gov.sa https://orcid.org/0000-0002-5864-084X 1 Regional Nursing Administration in Hail Region, Saudi Arabia The rise of Covid-19 cases became a worldwide outbreak and has made a great impact on the world population including nursing workforce. Search of related literature was conducted to gather data similar to the study. This review gives us a grip of the reality on what our nurses are experiencing in this time of pandemic. It gives a summary of the holistic view of the frontline nurses body response to their work, with great challenge to psychological and emotional aspects. http://pubs.sciepub.com/ajnr/8/5/10/ajnr-8-5-10.pdf Covid-19Pandemic nursing workforce mental distress compassion fatigue burn-out