eng Science and Education Publishing American Journal of Nursing Research 2378-5586 2018-10-09 6 6 437 445 10.12691/ajnr-6-6-11 AJNR20186611 article Eman Mohammed Eraky emymeraky@yahoo.com 1 Department of Maternal & Newborn Health Nursing, Faculty of Nursing, Cairo University, Cairo, Egypt Pregnant women are more vulnerable to VVC than healthy women with chronic recurrent candidiasis [1]. Supportive nursing instruction help pregnant women in improving their health by adopting preventive measures that help in reducing the incidence and avoid complication from VVC [2,3]. The aim of this quasi-experimental study was to examine the effect of supportive nursing instructions on recurrence of vulvovaginal candidiasis infection during pregnancy. A total of 100 pregnant women diagnosed as having vulvovaginal candidiasis infection who attend antenatal unit at El-Manial maternity hospital in Cairo, Egypt, were recruited for this study. The required data was collected through Semi-structured Interview questionnaire, pre-posttest questionnaire and VVC Follow-up Sheet. Results indicated that the age of the sample range was 18-45 year with a mean of 26.38± 6.56 years old, 64% living in urban area, 74% of the sample was negative smokers, 70% of the sample was housewife &48% of the sample had primary education. The results also revealed that a highly statistically significant difference between mean knowledge score regarding VVC during pregnancy in pretest and posttest (p<0.0001) and a highly statistically significant difference between level of knowledge regarding VVC during pregnancy in pre and posttest as (p<0.0001). Also, there was an observed relieve in majority of the symptoms of VVC infection after four weeks follow-up. In relation to recurrence of vulvovaginal candidiasis symptoms during pregnancy, the results revealed that most of cases did not develop recurrent episode of VVC attack during pregnancy through follow-up till term while minority of cases developed recurrent episode especially in third trimester of pregnancy. http://pubs.sciepub.com/ajnr/6/6/11/ajnr-6-6-11.pdf supportive nursing instruction recurrence of VVC during pregnancy