eng Science and Education Publishing American Journal of Nursing Research 2378-5586 2018-04-11 6 3 125 136 10.12691/ajnr-6-3-7 AJNR2018637 article Atyat Mohammed Hassan atyathassan@aun.edu.eg 1 Nahed Thabet Mohamed 1 Fayza Mohammed Mohammed 2 Eman Fathalla Gad 3 Lecturer of Pediatric & Premature Nursing, Faculty of Nursing, Assiut University Lecturer of Community Health Nursing, Faculty of Nursing, Assiut University Lecturer of Pediatrics, Faculty of Medicine, Assiut University Oral drug misuses are occurring at an alarming rate; these misuses are both avoidable and expensive to the healthcare system. Study aim: The aim was to evaluate the impact of an educational program for mothers about preventing oral medications misuse for children under five years. Design: Quiz-experimental research design was used. Setting: The study was implemented at out-patient clinics in Assiut University Children Hospital. Subjects: A convenience sample of 50 mothers who had children under five years with acute common illnesses. Tools: The study used two tools: Tool I included two parts; part one; the socioeconomic scale and part two; mothers' age and main sources of information. Tool II was the structured interview questionnaire about mothers' knowledge regarding their practices during oral medications administration. Results: The majority of the mothers (88%) had a poor score of knowledge about practice before the program while 94% of them had a good score after the program. Also, the majority of them (96%, 88%, and 78%) compared to 82%, 8%, and 14% respectively in the pre and posttest gave antipyretics, cough & cold and antibiotics medications without a prescription. Conclusion: The educational program improved the mothers' knowledge about practice regarding oral medications administration for their young children and decreased oral drug misuse with a statistically significant difference between pre and posttest as regard their total score. Recommendations: Pediatric hospitals should offer the mothers with handouts, brochures, pamphlets, posters or videotapes about oral medication administration. http://pubs.sciepub.com/ajnr/6/3/7/ajnr-6-3-7.pdf educational program drug misuse medications errors oral medications children under five years