eng Science and Education Publishing American Journal of Medical Sciences and Medicine 2327-6657 2020-09-09 8 4 153 156 10.12691/ajmsm-8-4-3 AJMSM2020843 article Onur Oral 1 George Nomikos 2 Nikitas Nomikos niknomikos@med.uoa.gr 3 4 Department of Health Sciences and Sports, Ege University Faculty of Sport Sciences, Izmir, Turkey Department of Orthopaedic Surgery, Chios Hospital, Chios, Greece School of Physical Education & Sport Science, National & Kapodistrian University of Athens Background: The study aims to investigate the effects of selective androgen receptor modulators (SARMs) among athletes and examine the possible beneficial results and risks of these substances for the athletes' health and performance and human health in general. Nowadays, SARMs have become a focus of interest in the world of sports and medicine. Because of their anabolic action, SARMs are considered quite promising for treating several disorders including breast cancer, osteoporosis, DMD (Duchenne Muscular Dystrophy), some type of tumors, etc. As for the athletic community, SARMs are used as doping for muscle mass increasing and strengthening and pose as an alternative to other steroid-based doping with their minimum side effects. SARMs are innovative substances for athletic performance and human health. Further study on SARMs is required in order to understand the long-term effects on human health and athletic performance. http://pubs.sciepub.com/ajmsm/8/4/3/ajmsm-8-4-3.pdf SARMs anabolic action testosterone doping