@article{ajmsm2016424,
author={Anyabolu, Ernest},
title={Prevalence and Associated Factors of Anemia in Treatment-na?ve HIV-positive Subjects in Southeast Nigeria},
journal={American Journal of Medical Sciences and Medicine},
volume={4},
number={2},
pages={41--46},
year={2016},
url={http://pubs.sciepub.com/ajmsm/4/2/4},
issn={2327-6657},
abstract={<b>Background and Objectives:</b> Anemia is an issue in human immunodeficiency virus (HIV) infection. This study was to determine the prevalence and associated risk factors of anemia in highly active anti-retroviral therapy (HAART)-na?ve, HIV-positive subjects in Owerri, Southeast Nigeria.<b> Methodology:</b> This was a cross-sectional study of HAART-na?ve HIV-positive subjects. Anthropometric and demographic data were collected. Hemoglobin (Hb) and other relevant investigations were performed. Anemia was defined, according to World Health Organization criteria, as Hb &lt;13.0g/dl in males and Hb &lt;12.0g/dl in females. Association of variables with anemia and the strength of variables to predict anemia were determined.<b> Results: </b>Mean Hb was 11.3¡À1.7g/dl in males and 11.1¡À1.9g/dl in females. Hb&lt;13.0g/dl was present in 66.4% of males, while Hb&lt;12.0g/dl was present in 67.8% of females. Overall, Hb¡Ý12.0g/dl was present in 128(32.6%), Hb&lt;12.0g/dl in 252(67.4%), Hb 11.0-12.0g/dl in 177(45.0%), Hb 8.0-10.9g/dl in 82(20.9%) and Hb&lt;8.0g/dl in 6(1.5%) of the HIV subjects. Body mass index (BMI) and cluster of differentiation 4 (CD4) cells count predicted hemoglobin, while underweight, BMI, CD4 cells count &lt;200/ml, spot urine protein (SUP) and 24-hour urine protein (24HUP) predicted anemia in HIV-positive subjects.<b> Conclusion: </b>The prevalence of anemia was high (67.4%) in HAART-na?ve HIV-positive subjects. BMI and CD4 cells count were predictors of hemoglobin in HIV-positive subjects. CD4 cells count &lt;200, underweight, BMI, 24HUP and SUP were predictors of anemia in HAART-na?ve HIV-positive subjects. Abnormalities of weight changes and renal function were common in HAART-na?ve HIV-positive subjects who were anemic in Owerri, Southeast Nigeria. Anemic HAART-na?ve HIV-positive subjects should be evaluated at the early stages of the infection for underweight and renal damage.},
doi={10.12691/ajmsm-4-2-4}
publisher={Science and Education Publishing}
}