eng Science and Education Publishing American Journal of Medical Sciences and Medicine 2327-6657 2014-11-27 2 6 131 133 10.12691/ajmsm-2-6-4 AJMSM2014264 article Salil Vaniawala 1 Pankaj Gadhia pankajkgadhia@gmail.com 1 Molecular Cytogenetic Unit, S.N. Gene Laboratory and Research Centre, President Plaza-A, Near RTO circle, Surat, India Edward syndrome is rare in live births in comparison to most common Down and Patau syndromes. The estimated incidences are one in 6000 live births and interestingly 70 to 80% those affected are females. The occurrence of double aneuploidy involving XXY + 18 is very rare in live born however, most of cases are available with spontaneous abortions. Here, we report a 07 day a male infant with typical features of Edward syndrome such as microcephaly and low set of ears having mosaic double aneuploidy with Klinfelter syndrome. http://pubs.sciepub.com/ajmsm/2/6/4/ajmsm-2-6-4.pdf double aneuploidy mosaic Edward syndrome Klinfelter syndrome