Science and Education Publishing American Journal of Medical Sciences and Medicine 2327-6657 2 4 2014 08 31 Comprehensive Analysis of Laboratory Results of a Sjögren's Syndrome Patient Combining Autoimmune Hepatitis with Double Negatives of the Sjögren's Ayndrome Antigen A and B 67 70 EN Jianwei Zhou Medical Laboratory, Affiliated Hospital of Jining Medical College, Shandong Province, Jining City, PR China Cui Kong Zhaocai Zhang Xinke Chen Shuo Shi Liang Han AJMSM2014241 10.12691/ajmsm-2-4-1 2014 08 04 2014 08 27 2014 08 31 Objective: To analyze the laboratory results of a Sjögren's syndrome combining autoimmune hepatitis (SS-AIH) with double negative of SSA and SSB (SSA-SSB-). Methods: 10 ml venous blood was collected from the patients, and the blood routine, biochemical and immunological indices were respectively detected. Results: The values of WBC, neutrophiles, ESR, ALT, AST, CRP, IgA and IgG were beyond the corresponding reference ranges, respectively. The antinuclear antibody pattern was nuclear homogenous with the titer of 1:1000. The antibodies to PM-Scl, AnuA and Rib-P were all positive. In the fluorescence immune test for AIH, anti-mitochondrial antibodies (AMA) was positive. The concentration of CCP was 92.5 U/ml which also was beyond the reference range. Conclusion: There are certain changes in the laboratory results for the SS-AIH patient with SSA-SSB-, and if the changes are the common characters for this kind of disease need further observations in future.