eng Science and Education Publishing American Journal of Medical Sciences and Medicine 2327-6657 2014-08-31 2 4 67 70 10.12691/ajmsm-2-4-1 AJMSM2014241 article Jianwei Zhou immunolife@126.com 1 Cui Kong 2 Zhaocai Zhang 2 Xinke Chen 2 Shuo Shi 2 Liang Han 2 Medical Laboratory, Affiliated Hospital of Jining Medical College, Shandong Province, Jining City, PR China Nursing Department, Affiliated Hospital of Jining Medical College, Shandong Province, Jining City PR China Objective: To analyze the laboratory results of a Sjögren's syndrome combining autoimmune hepatitis (SS-AIH) with double negative of SSA and SSB (SSA-SSB-). Methods: 10 ml venous blood was collected from the patients, and the blood routine, biochemical and immunological indices were respectively detected. Results: The values of WBC, neutrophiles, ESR, ALT, AST, CRP, IgA and IgG were beyond the corresponding reference ranges, respectively. The antinuclear antibody pattern was nuclear homogenous with the titer of 1:1000. The antibodies to PM-Scl, AnuA and Rib-P were all positive. In the fluorescence immune test for AIH, anti-mitochondrial antibodies (AMA) was positive. The concentration of CCP was 92.5 U/ml which also was beyond the reference range. Conclusion: There are certain changes in the laboratory results for the SS-AIH patient with SSA-SSB-, and if the changes are the common characters for this kind of disease need further observations in future. http://pubs.sciepub.com/ajmsm/2/4/1/ajmsm-2-4-1.pdf Sjögren's syndrome autoimmune hepatitis SSA SSB