Science and Education Publishing American Journal of Medical Sciences and Medicine 2327-6657 2 1 2014 01 20 The Prevalence of Skeletal Malocclusion in the Southern Aseer Region of Saudi Arabia 13 15 EN Mazen Almasri Oral Maxillofacial Surgery, Umm Alqura Uni - Makka city, Saudi Arabia AJMSM2014213 10.12691/ajmsm-2-1-3 2013 12 27 2014 01 09 2014 01 20 Objective: to study the prevalence of skeletal malocclusion (SMO) cases in the orthodontic and maxillofacial surgery unit of King Khalid university health center / Aseer central Hospital (KKUHC) in the southern Aseer region of Saudi Arabia (SSA) where no previous epidemiological data took place. Materials and methods: A retrospective chart review of all the cases visiting the orthodontic / maxillofacial surgery unit at KKUHC from September 2010 to August 2012 was reviewed. All the pertinent data were extracted and tabulated for investigation while incomplete records were eliminated. Results: A total of 364 completed charts were included in the study and all the pertinent data were extracted and tabulated. It was found that 42% of the cases had skeletal malocclusion (SMO) while 58% had dental maocclusion only. Class 3 SMO represented the majority of the cases scoring 49% of the records. The female to male ratio was 1:3.2, which is significantly lower than other recorded studies. Conclusion: SMO deformity was found to be a common presentation in the SSA health care center where class 3 comprised the majority unlike other areas in the country.