@article{ajmr2016443,
author={{Akhtar, Nayareen and Rahman, Rezwanur and Sultana, Shahin},
title={Antimicrobial Sensitivity Pattern of <i>Escherichia coli </i>Causing Urinary Tract Infection in Bangladeshi Patients},
journal={American Journal of Microbiological Research},
volume={4},
number={4},
pages={122--125},
year={2016},
url={http://pubs.sciepub.com/ajmr/4/4/3},
issn={2328-4137},
abstract={<b>Objectives</b>: Urinary tract infection (UTI) is a common bacterial infection in the Bangladesh community. There has been an increasing resistance by <i>Escherichia coli</i> to the commonly available antibiotics. The aim of the present study was to determine the prevalence of UTI, the common causative bacteria &amp; antimicrobial susceptibility patterns of <i>E. coli</i> responsible for urinary tract infections (UTIs) to currently used antimicrobial agents. <b>Methods</b> <b>and Results:</b> In this study, three hundred urine specimens from clinically suspected UTI patients were collected from both outpatient and inpatient department during the period of February 2015 to January 2016 from a tertiary level hospital in the central part of country. The inclusion criteria included patients presenting with symptoms suggestive of UTI at the study site and who gave informed written consent to participate in the study. The exclusion criteria included patients on antibiotics within the last 2 weeks, and those with recent history of instrumentation. The urine samples received were processed using standard methods. Antimicrobial sensitivity patterns were performed on all <i>E. coli </i>isolates obtained from urine samples by disc diffusion method. Among 300 urine samples, (59%) yielded significant bacteriuria; 123 samples (41%) showed no growth. Out of 177 urine samples which showed significant bacterial growth, 72 (40.7%) samples comprised of males and 105 (59.3%) of females. Females within the age group of 20¨C29 years(26.67%) and elderly males of ¡Ý60 years(34.7%) showed higher prevalence of UTI. 75.7% of isolates were found to be <i>Escherichia coli</i>, 7.9% <i>Klebsiella pneumoniae</i>, 5.6% <i>Proteus mirabilis, Pseudomonas aeruginosa</i> 5.1%, 1.7% <i>Enterococci faecalis, </i>2.8% <i>Staphylococci saprophyticus </i>and 1.1% were <i>Staphylococcus aureus</i>. <i>E. coli </i>as the predominant cause of UTI, showed the highest percentage of resistance to co-trimoxazole, nalidixic acid and amoxicillin. The isolates were most sensitive to Imipenam, Meropenam, Nitrofurantoin and Amikacin. <i>Klebsiella pneumoniae </i>was the second most prevalent pathogen. <b>Conclusion: </b><i>E. coli </i>was the most frequent isolate. Imipenam, Meropenam, Nitrofurantoin and Amikacin were shown to be very effective against <i>E. coli</i> organisms.},
doi={10.12691/ajmr-4-4-3}
publisher={Science and Education Publishing}
}