@article{ajmr20251322,
author={{Monon, KONE and Daouda, TOURE and Philomene, KOKORA Aya and Roland, KOFFI Kouadio Guy and Abdoulaye, TOURE and Karamoko, OUATTARA and Adama, COULIBALY},
title={Evaluation of the Antibacterial Activity of Extracts of Alchornea Cordifolia (Schum Et Thonn Mull) Leaves on the in Vitro Growth of Ureolytic Germs Isolated from Urethral Samples At the Korhogo Rural Hospital Centre, North C?te d¡¯Ivoire},
journal={American Journal of Microbiological Research},
volume={13},
number={2},
pages={28--32},
year={2025},
url={https://pubs.sciepub.com/ajmr/13/2/2},
issn={2328-4137},
abstract={The germs involved in urinary tract infections are a major concern for clinicians. The increasing multi-resistance of these bacteria to conventional antibiotics is a real public health problem. The aim of this study was to contribute to the treatment of urinary tract infections using the leaves of <i>Alchornea</i><i> </i><i>cordifolia</i>. The leaves were subjected to two extraction methods (infusion and hydro-ethanolic maceration). A tri-phytochemical analysis using colorimetry and tube precipitation revealed the polyphenol composition of the extractsThe sensitivity of the extracts was assessed by agar well diffusion and the antibacterial parameters determined by diffusion in liquid medium followed by spreading on Mueller Hinton agar. The results showed that the extracts were rich in sterols, polyterpenes, polyphenols, flavonoids, tannins, alkaloids and saponins, and possessed interesting antibacterial activity. All strains were sensitive to extremely sensitive to <i>A.</i><i> </i><i>cordifolia</i> extracts at 50 mg/ mL. Low MIC values ranging from 0.78 to 12.5 mg/mL were recorded. All the extracts had a bactericidal effect on all the strains tested. This plant has good antibacterial activity and is therefore a good candidate for the treatment of urinary tract infections.},
doi={10.12691/ajmr-13-2-2}
publisher={Science and Education Publishing}
}