Science and Education Publishing American Journal of Microbiological Research 1 1 2013 04 28 Protease Production by Fusarium oxysporum in Solid- State Fermentation Using Rice Bran 45 47 EN Syed Sajeed Ali Department of Microbiology, Shri Shivaji Science College Amravati, Amravati, India N.N. Vidhale AJMR2013132 10.12691/ajmr-1-3-2 2012 12 30 2013 04 26 2013 04 28 Agroindustrial wastes constitute valuable source for microbial cultivation and enzyme production. An attempt was made to study protease production by Fusarium oxysporum on agroindustrial waste rice bran under solid-state fermentation. Rice bran obtained from rice mill has proved to be efficient substrate for enzyme production by F. oxysporum. To study the maximum enzyme production the process parameters of fermentation where optimized. Maximum protease production i.e. (70.5U/g) was obtained with an initial moisture content of 50% (w/w) on incubation period of 72h at 35ˇăC temperature with initial pH of substrate 7.0. The above data revealed that agroindustrial waste rice bran and optimized condition of solid-state fermentation can be successfully employed for protease production by Fusarium oxysporum.