eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2021-04-19 9 7 378 379 10.12691/ajmcr-9-7-10 AJMCR20219710 article Omar Rafa orafa@student.touro.edu 1 2 Aaron Campeas 2 2 Eric J. Basile 2 2 Hackensack Meridian Health Hackensack University Medical Center NJ 07601, United States Colonoscopies are performed in order to screen for and identify gastrointestinal malignancies, underlying colonic bleeds, and structural anomalies or defects. Though the procedure largely has few complications, some of the potential adverse outcomes include splenic laceration, colonic perforation, hemorrhage due to prolonged bleeding from biopsy sites, generalized abdominal bloating and pain, and anesthesia-related adverse reactions. In this paper, we present a case of grade 3 splenic laceration post routine colonoscopy. Splenic lacerations range in presentation from completely asymptomatic, non-life-threatening to immediate hemodynamic instability. It is vitally important to recognize this potential complication clinically because proper management and timely recognition has the potential to improve survival outcomes. http://pubs.sciepub.com/ajmcr/9/7/10/ajmcr-9-7-10.pdf colonoscopy splenic laceration gastroenterologist