eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2021-03-30 9 6 339 341 10.12691/ajmcr-9-6-9 AJMCR2021969 article Eric J. Basile Ebasile@student.touro.edu 1 2 Aaron Campeas 2 Omar Rafa 2 Autumn Breutzmann 2 Touro College of Osteopathic Medicine, NY, New York, United States A 57-year-old male presented to an outpatient Multiple Sclerosis (MS) clinic for excruciating spastic pain secondary to MS. After a trial of multiple pain management drugs with no success, he began a trial of marijuana. In this paper, we report the extent of improvement in quality of life secondary to cannabinoid use after failing multimodal pain management regimens. http://pubs.sciepub.com/ajmcr/9/6/9/ajmcr-9-6-9.pdf multiple sclerosis pain management medicinal marijuana cannabinoids