eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2021-02-24 9 5 281 285 10.12691/ajmcr-9-5-5 AJMCR2021955 article Ahmed Hashim ahmed.m.hashim89@gmail.com 1 Raai Mahmood 1 Mohamedanwar Ghandour 2 Hammam Shereef 2 Ammar ELJack 3 Cecilia Big 4 Kevin Jamil 5 Rajiv John 5 Department of Internal Medicine, Beaumont Health- Dearborn, MI, USA Division of Nephrology, Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, USA Division of Cardiology, Department of Internal Medicine, Baylor- Scott/white heart hospital, Plano, Tx, USA Division of Infectious Diseases, Department of Internal Medicine, Beaumont Health- Dearborn, MI, USA Division of Thoracic Surgery, Beaumont Health- Dearborn, MI, USA We report a case of Sternoclavicular Joint (SCJ) infection in a 52-year-old male who developed an empyema over six days. During the first three visits, he had worsening pectoral and shoulder pain and was symptomatically treated and discharged. During the first ED visit, a computed tomography (CT) scan of the neck was negative. During the second ED visit, CTA chest was negative for pulmonary embolism. Three days later, CTA of the neck showed density from the left first rib to the left sternoclavicular joint, suggesting a hematoma. During the final ED visit, CT of the chest showed a left anterior chest wall abscess contiguous with a left upper lobe empyema. VATS confirmed empyema and revealed costochondral and SCJ abscess. Decortication, SCJ resection, and pectoralis muscle debridement were performed. Methicillin-susceptible Staphylococcus Aureus (MSSA) was isolated from surgical cultures. After the pectoralis muscle flap closure, he was treated with IV cefazolin for a total of six weeks. Health care professionals should have a high index of suspicion for SCJ infections in patients with a similar clinical presentation. This case highlights the importance of early and prompt diagnosis of MSSA SCJ infections to prevent sequelae of the disease. http://pubs.sciepub.com/ajmcr/9/5/5/ajmcr-9-5-5.pdf sternoclavicular joint video-assisted thoracoscopic surgery decortication