eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2021-09-05 9 12 690 692 10.12691/ajmcr-9-12-7 AJMCR20219127 article Mehdi Seyedmoradi 1 Niloufar Mohamadian 1 Mazaher Ramezani mazaher_ramezani@yahoo.com 2 3 Young Researchers and Elite Club, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Lymphocyte-predominant Hodgkin¡¯s lymphoma (LPHL) that involving the breast and axillary tissue is very rare. We report a case of this subtype of Hodgkin¡¯s lymphoma (HL) in right breast mass of a 48-year-old man, who presented with a 20 years history of this breast painless mass; but over the past year there has been an increase in the size of the mass, with pain but no discharge. Pathology report after immunohistochemistry (IHC) confirmed the LPHL. http://pubs.sciepub.com/ajmcr/9/12/7/ajmcr-9-12-7.pdf Hodgkin¡¯s lymphoma Lymphocyte-predominant Hodgkin¡¯s lymphoma LPHL