eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2021-08-26 9 12 675 677 10.12691/ajmcr-9-12-3 AJMCR20219123 article Houcine Mrad 1 2 Wided Besle? 2 2 Warda Mahdhaoui 2 2 Salem Bouomrani salembouomrani@yahoo.fr 2 2 Department of Internal medicine, Military Hospital of Gabes, Gabes 6000, Tunisia Cardiac complications of brucellosis are extremely rare with an overall frequency estimated at less than 1%. They are dominated by endocarditis and myocarditis, while pericarditis remains exceptional and unusual with only few sporadic cases in the world literature. Brucella pericarditis is exceptionally isolated. It is often associated with the involvement of other cardiac tunics (endocarditis and/or myocarditis) or is part of a complex cardiac involvement (brucella pancarditis). This clinical presentation of brucellosis is a real diagnostic challenge for clinicians. We report an original case of acute pericarditis as the first and only manifestation revealing septicemic brucellosis in 27-year-old Tunisian woman. http://pubs.sciepub.com/ajmcr/9/12/3/ajmcr-9-12-3.pdf acute pericarditis brucellosis heart pericardium brucella