@article{ajmcr202191215,
author={{Heuvelhorst, Kara L and Diener, Tyler and Manzoor, Hana and Khadra, Maher and Musa, Faisal and Jafri, Syed K},
title={Cerebral Venous Sinus Thrombosis without Thrombotic Thrombocytopenic Syndrome in a Male Patient after Ad26.COV2.S Vaccination},
journal={American Journal of Medical Case Reports},
volume={9},
number={12},
pages={719--721},
year={2021},
url={http://pubs.sciepub.com/ajmcr/9/12/15},
issn={2374-216X},
abstract={Objective: Here we present one of the first cases of Janssen (Johnson & Johnson Ad26.COV2.S vaccine-associated cerebral venous sinus thrombosis (CVST) in a male patient, and the presumed first case without associated thrombotic thrombocytopenic syndrome (TTS). Method: Patient was identified as a vaccine-related adverse effect due to the unusual presentation of CVST in a male following COVID-19 vaccination, though without thrombocytopenia. Results: Patient presented with left-sided weakness and transient dysarthria. Imaging revealed extensive CVST. Thorough coagulopathy work-up was negative and platelet levels remained within the normal range. Patient improved with non-heparin anticoagulation. Discussion: As more people worldwide continue to be vaccinated against COVID-19, the incidence of vaccine-related complications can be expected to rise. Multiple cases of CVST have been reported in patients following COVID-19 vaccination with associated TTS, nearly all in women. However, this is not the only presentation. Cerebral venous sinus thrombosis should be a consideration in patients who present with headache or altered mental status after COVID vaccination, despite normal platelet levels.},
doi={10.12691/ajmcr-9-12-15}
publisher={Science and Education Publishing}
}