Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

A Case of Rumpel-Leede Phenomenon in Ulnar Artery Catheterization

Pramod Theetha Kariyanna, Amog Jayarangaiah, David D. Song, Apoorva Jayarangaiah, Sushruth Das, Ashkan Tadayoni, Samy I. McFarlane*

Division of Hematology-Oncology, Department of Internal Medicine, Albert Einstein College of medicine/ Jacobi Medical Center, Bronx, N.Y.-10461, U.S.A.

Abstract: Rumpel - Leede phenomenon (RLP) was described as early 1909 by Theodore Rumpel and by Stockbridge Leede in 1911 in patients suffering from scarlet fever. Acute development of petechial rashes distal to the application of blood flow occlusive devices such as a blood pressure cuff or tight wrapped bandage, is a typical finding in this phenomenon. Multiple isolated cases of RLP associated with coronary angiogram have been reported. In this report, we present a case of a 53-year-old male who developed RLP after percutaneous intervention of the proximal-mid left anterior descending artery after application of a sphygmomanometer cuff to contain a right forearm hematoma and application of a trans-radial band. We here discuss the etiopathogenesis and management of RLP that develops post coronary angiogram.

Keywords: Rumpel - Leede phenomenon, coronary angiogram, Ulnar Artery Catheterization, petechial rash, TR band, forearm hematoma

Received April 23, 2021; Revised May 27, 2021; Accepted June 08, 2021

Citation: Pramod Theetha Kariyanna, Amog Jayarangaiah, David D. Song, Apoorva Jayarangaiah, Sushruth Das, Ashkan Tadayoni, Samy I. McFarlane, A Case of Rumpel-Leede Phenomenon in Ulnar Artery Catheterization. American Journal of Medical Case Reports, 9 (10). 495-498. January 2021. doi:10.12691/ajmcr-9-10-4

1. Introduction

Rumpel-Leede phenomenon (RLP) was described as early 1909 by Theodore Rumpel and Stockbridge Leede in 1911 in patients suffering from scarlet fever [1]. Acute development of petechial rashes distal to blood flow occlusive devices such as a blood pressure cuff or a tight wrap bandage is a typical finding in this phenomenon. RLP is mostly benign and resolves with conservative management. Multiple isolated cases of RLP associated with coronary angiogram have been reported in recent years. Here we present a case of RLP in a patient after an elective coronary angiogram performed via tight ulnar artery access. The procedure was complicated by a small forearm hematoma which was conservatively managed by application of a sphygmomanometer cuff to contain and stop the bleeding, following which RLS was noted. We here present the case and discuss the pathogenesis and management.

2. Clinical Presentation

A 53-year-old male with a history of diabetes mellitus, hypertension, hyperlipidemia and smoking was referred for a diagnostic coronary angiogram by his primary doctor. The patient had presented to his primary care doctor with typical angina on exertion, hence a nuclear stress test which was performed showed moderate anteroseptal ischemia. On the day of presentation, he was afebrile, heart rate was 77 beats/minute, blood pressure was 127/82 and respiratory rate was 16 cycles/min. The patient had no significant findings on physical examination, however, a weak right radial pulse of 1+ was noted. The patient’s complete blood count, complete metabolic profile and coagulation profile revealed no abnormal findings, and the pertinent values have been tabulated (Table 1). Hence a decision was made to perform a coronary angiogram using right ulnar artery access using ultrasound guidance. Prior to the angiogram, the patient was loaded with appropriate DPT with aspirin and plavix and high intensity statin (Rosuvastatin 40mg). Coronary angiogram revealed a >95% obstruction of the mid LAD (Figure 1). A successful PCI of the proximal to mid LAD was performed and a right ulnar TR band was applied. In the post-operative unit 30 minutes after the procedure, the patient was noted to have a small forearm swelling and was diagnosed with a right forearm hematoma due to coronary angiogram. In order to contain the forearm hematoma, a sphygmomanometer cuff was applied, 30 minutes after, it was noted that the hematoma had resolved, however, the patient was noted to have a newly formed petechial rash on the dorsal aspect of the right palm (Figure 2), hence a diagnosis of RSL was established. The sphygmomanometer cuff was released immediately after the rashes were noted. The petechial rashes completely resolved 2 days later without any further intervention.

Table 1. Pertinent laboratory values of the patient on admission

Figure 1. Coronary angiogram showing greater than 95% obstruction of the proximal-mid left anterior descending artery (left) and successful drug eluting placement in the lesion (right)

Figure 2. Rumpel-Leed phenomenon on the dorsal aspect of the right palm

3. Discussion

Multiple cases of RLP associated with coronary angiogram have been reported, the findings of which are summarized in Table 2 [2,3,4,5,6]. RLP has been typically reported in literature after prolonged blood pressure inflations, however, multiple other conditions are known to cause RLP (Table 3) (Figure 3) [7]. Increased capillary fragility, antiplatelet and anticoagulation during the procedure, arterial occlusion due to vascular access sheaths, venous and capillary hypertension due to compressive devices such as trans-radial bands or sphygmomanometer cuffs, venous compression due to forearm/arm hematomas are contributing factors for the development of RLP post-coronary angiogram [2,3,4,5,6]. RLP sign is mostly benign and represents ruptured capillaries leading to petechiae formation [2,3,4,5,6]. RLP is not associated with any major complications or limb loss, and hence rarely demands any intervention directed to reverse the petechiae. Anticoagulation and antiplatelet therapy can be safely continued in these patients after percutaneous coronary intervention. Anticoagulation and antiplatelet reversal is not needed if RLP is observed. Venous return should be facilitated by prompt pressure release in arterial occlusive devices and gentle pressure should be applied over any arm or forearm hematoma to avoid venous/capillary hypertension.

Table 2. Summary of reported cases of Rumpel-Leede phenomenon reported post coronary angiogram

Table 3. Conditions associated with RLP [7]

Figure 3. Etiopathogenesis of Rumpel-Leede phenomenon after coronary angiogram

4. Conclusion

RLP post coronary angiogram is a benign phenomenon that can be conservatively managed. RLP does not demand anticoagulation or antiplatelet reversal and resolves spontaneously upon prompt venous decongestion and hematoma management.

References

[1]   | Wang, K., & Lee, J. (2014). Images in clinical medicine. Rumpel-Leede sign. The New England journal of medicine, 370(1), e1.
[2]   | Rattka, M., & Rottbauer, W. (2018). Rumpel-Leede Sign After Coronary Angiography. Deutsches Arzteblatt international, 115(6), 82.
[3]   | Khoury Abdulla, R., & Safian, R. D. (2018). Rumpel–Leede Phenomenon After Radial Artery Catheterization. Circulation: Cardiovascular Interventions, 11(4), e006507.
[4]   | Sud, M., & Madan, M. (2018). Rumpel-Leede Phenomenon: Acute Dermal Capillary Rupture Complicating Radial Artery Cannulation. JACC: Cardiovascular Interventions, 11(18), 1900-1901.
[5]   | Van Rhijn, B. D., Vlachojannis, G. J., & Balak, D. M. W. (2019). Petechial purpuric rash after non-invasive blood pressure measurement: Rumpel-Leede sign. BMJ case reports, 12(10).
[6]   | Toufaily, A. I., & El Sayed, A. A (2020). Rumpel-Leede phenomenon after brachial artery catheterization. Case Report - Interventional Cardiology (2020) 12(4).
[7]   | Sharma, A., Jharaik, H., & Sharma, R. (2019). Rumpel-Leede (RL) phenomenon. Journal of Medical Science And Clinical Research, 7(6).