eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2020-10-14 9 1 4 8 10.12691/ajmcr-9-1-2 AJMCR2021912 article Shaidaton Nisha 1 Syeda Saima Alam 2 Md. Nahian Rahman 2 Khaleda Islam 3 MSc, Institute of Nutrition and Food Science, University of Dhaka, Bangladesh Lecturer, Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Bangladesh Professor, Institute of Nutrition and Food Science, University of Dhaka Thalassemia is an autosomal recessive disease. According to the WHO data, there are 269 million carriers of thalassemia worldwide, out of which 40 million are in South East Asia. This study was conducted with the primary objective to assess physiological and mental health condition of patients with thalassemia at a tertiary care hospital. It has been noticed by the study that there are frequent chances of diseases among thalassemia patients as the assessment found 20% of study patients jaundice manifested at least one time on their lifetime, 19% cardio-vascular disease, 18% hepatic diseases, 15% fever, 12% respiratory problems, 10% kidney disease and 6% diarrhoea. According to age category our study found that 18 to 25 years age category had 15.4% chances of having diseases, 26 to 30 years age category had 14.3% chances, 31 to 35 and 36 to 40 years age category had 24.6% and 42% chances of having diseases. It clearly indicates that increase in age increases the chances of disease occurrence. In our study, 57.5% patients with thalassemia manifested depression comprising 19.5% chronic depression, 20.3% minimal depressed, 8.5% mild and 9.1% moderately depressed. This study found that patients with thalassemia face mental health problems which requires planning of authorities and experience consultants to educate the life skill and to survive in a healthful manner. http://pubs.sciepub.com/ajmcr/9/1/2/ajmcr-9-1-2.pdf morbidity pattern mental health patients thalassemia physiological and mental health conditions