eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2020-11-05 9 1 57 61 10.12691/ajmcr-9-1-14 AJMCR20219114 article Yotam Kolben yotamkol@hadassah.org.il 1 Yuval Ishay 1 Henny Azmanov 1 Matan Fischer 2 Nir Pillar 3 Simona Grozinsky-Glasberg 4 Department of Medicine, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel Department of Endocrinology, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel Department of Pathology, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel Neuroendocrine Tumor Unit, ENETS Center of Excellence, Department of Endocrinology, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel We present the case of a young male patient who arrived at the emergency room due to headache, constitutional and gastrointestinal symptoms. Upon presentation and during hospitalization, a complex clinical and chemical picture unfolded, and several diagnoses were considered. Eventually, it was concluded that panhypopituitarism secondary to craniopharyngioma was the cause of his symptoms. This long-standing condition was unmasked by an acute infection with Parvovirus. Treatment with hormone replacement therapy brought prompt improvement in both laboratory values and clinical condition. http://pubs.sciepub.com/ajmcr/9/1/14/ajmcr-9-1-14.pdf parvovirus craniopharyngioma hypopituitarism