eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2020-05-29 8 9 277 280 10.12691/ajmcr-8-9-6 AJMCR2020896 article Yuvraj Singh Chowdhury 1 Rishard Abdul 1 Pramod Theetha Kariyanna 1 Apoorva Jayarangaiah 2 Mrinali Shetty 3 Clara Wilson 3 Naureen Kabani 3 Jonathan D. Marmur 3 Alan Feit 3 Moro O. Salifu 3 Isabel M. McFarlane Isabel.McFarlane@downstate.edu 3 Department of Internal Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, N.Y, USA - 11203 Department of Internal Medicine, Albert Einstein College of Medicine, NYC + HHC Jacobi Medical Center, 1400 Pelham Pkwy S, Bronx, NY, USA- 10461 Division of Cardiovascular Disease and Department of Internal Medicine, University of Chicago- Northshore University Health Systems, Chicago, IL, USA - 60631 Coronary artery ectasia (CAE) is defined by the Coronary Artery Surgery Study (CASS) registry as the aneurysmal dilatation 1.5 times the diameter of a coronary artery compared to the adjacent normal coronary artery. CAE is reported with a prevalence of 1.2% - 4.9%. Most CAEs are attributed to atherosclerosis or post-percutaneous coronary intervention (PCI) vessel injury. Vasculitides and infection are uncommon etiologies. A review of 59,423 patients from the Danish registry demonstrated a 3-fold increase in the prevalence of abdominal aortic aneurysms in patients with concomitant severe psoriasis. We present a case of a 64-year-old male with severe plaque psoriasis complaining of substernal chest pain whose coronary angiography demonstrated CAE of the left anterior descending and circumflex arteries. Due to its pro-inflammatory state, psoriasis is associated with various systemic manifestations including cardiac and vascular complications. With possibly a similar underlying pathophysiological mechanism, we describe to the best of our knowledge the first case of CAE in a patient with severe psoriasis. http://pubs.sciepub.com/ajmcr/8/9/6/ajmcr-8-9-6.pdf coronary artery ectasia psoriasis inflammation atherosclerosis abdominal anerurysms