eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2020-07-26 8 11 413 417 10.12691/ajmcr-8-11-9 AJMCR20208119 article Mousa Suhail Abu Ghoush mousasuhail@hotmail.com 1 Abdulla Alhassani 2 Alaa Alkhazraji 3 Syed Hussaini 4 Zayed Military Hospital, Internal Medicine Resident, Abu Dhabi, United Arab Emirates Zayed Military Hospital, Consultant Gastroenterology and Head of Department, Abu Dhabi, United Arab Emirates Zayed Military Hospital, Consultant Internal Medicine, Abu Dhabi, United Arab Emirates Zayed Military Hospital, Consultant Internal medicine, United Arab Emirates Background: Eosinophilic gastroenteritis is a rare disease of the gastrointestinal tract that may involve some or all of its layers.It may have a varied presentation and is characterized by eosinophilic infiltration. The diagnosis is typically confirmed by biopsy, which should reveal 20-25 eosinophils per high-power field on microscopic examination. Case Presentation: We report a 25 years old man who presented with acute abdominal pain and diarrhea. He was found to have moderate ascites on abdominal US. The investigations revealed peripheral eosinophilia with markedly elevated eosinophils (96%) in the ascitic fluid. The imaging studies showed diffuse concentric bowel wall thickening involving the entire small bowel and Colon. The diagnosis was confirmed by biopsy from the duodenum, terminal ileum and colon. The patient was managed with steroids. Conclusions: This case report highlights a rare entity of Eosinophilic gastritis, which is eosinophilic gastroenterocolitis, diagnosis is confirmed via histopathology along with clinical presentation and exclusion of other causes of tissue eosinophilia. http://pubs.sciepub.com/ajmcr/8/11/9/ajmcr-8-11-9.pdf Eosinophilic gastroenteritis biopsy steroids case report