eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2020-07-16 8 11 386 388 10.12691/ajmcr-8-11-2 AJMCR20208112 article Mousa Suhail Abu Ghoush mousasuhail@hotmail.com 1 Zayed Military Hospital, Internal Medicine, Abu Dhabi, United Arab Emirates Background: Hereditary neuropathy with liability to pressure palsies (HNPP) is an uncommon diagnosis that should be considered in patients with multiple compressive neuropathies. This case reports highlights a relatively rare neuropathy with genetic and occupational predisposition, probably first to be reported in the united arab emirates. Case Presentation: We present the case of a 41 years old male who presented with right hand numbness and weakness. Electrodiagnostic testing revealed multifocal neuropathy. Subsequent genetic testing identi?ed heterogeneous deletion of the PMP22 gene to con?rm the diagnosis of HNPP. Conclusions: Hereditary neuropathy with liability to pressure palsies can present as a multifocal neuropathy. Occupational history along with genetic testing plays a pivotal role to make the diagnosis. http://pubs.sciepub.com/ajmcr/8/11/2/ajmcr-8-11-2.pdf hereditary neuropathy with liability to pressure palsies compressive neuropathies genetic testing