eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2019-11-14 8 1 11 13 10.12691/ajmcr-8-1-3 AJMCR2020813 article Derek J. Estes destes@med.miami.edu 1 Winnie Szeto 2 Michael Kingsley 3 Julio Cesar Poveda 3 Thiago Beduschi 3 Amar R. Deshpande 3 Division of Gastroenterology and Hepatology, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA 3Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA Drug-induced autoimmune hepatitis (DI-AIH) is a poorly defined, underreported liver disorder. This report describes a rare case of anti-TNF DI-AIH in a patient with Crohn’s disease resulting in acute liver failure requiring orthotopic liver transplantation in which a novel technique of leveraging a delayed abdominal fascial closure to perform ileocolonic anastomotic revision was used. http://pubs.sciepub.com/ajmcr/8/1/3/ajmcr-8-1-3.pdf Crohn’s disease drug-induced liver injury (DILI) inflammatory bowel disease (IBD) infliximab orthotopic liver transplantation