eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2019-09-15 7 12 305 307 10.12691/ajmcr-7-12-1 AJMCR20197121 article Mehlika İşcan mehlikaiscan@gmail.com 1 İsmail Sarbay 1 Şebnem Batur 2 Akif Turna 2 İstanbul University, Cerrahpasa Medical Faculty, Department of Thoracic Surgery, İstanbul, Turkey İstanbul University, Cerrahpasa Medical Faculty, Department of Pathology, İstanbul, Turkey The mediastinum is a rare localization, as it has been reported in a few cases in the literature for hamartoma, which is a benign tumor. The treatment is surgical resection when an image consistent with anterior mediastinum is observed. In addition, thymoma resection may provide remission in Myasthenia Gravis as it is frequently seen with Myasthenia Gravis and Thymoma. In this case, we submitted our case in which we have resected the anterior mediastinal lesion by applying biportal extended VATS thymectomy in the patient of Myasthenia Gravis with pre-diagnosis of thymoma. Remarkably, the pathology of our case was reported as Hamartoma, and the postoperative six-month follow-up has also indicated regression of Myasthenia Gravis disease. http://pubs.sciepub.com/ajmcr/7/12/1/ajmcr-7-12-1.pdf hamartoma myasthenia gravis VATS thymectomy