@article{ajmcr2019713,
author={{Jayarangaiah, Apoorva and Kariyanna, Pramod Theetha and Chokshi, Tanuj and Srinivasan, Maya and Asun, Seline and Ashamalla, Michael and Youssef, Irini and McFarlane, Samy I},
title={Leukocytosis Associated with Esophageal Squamous Cell Carcinoma as a Predictor of Poor Prognosis - A Case Report and Review of Literature},
journal={American Journal of Medical Case Reports},
volume={7},
number={1},
pages={9--12},
year={2019},
url={http://pubs.sciepub.com/ajmcr/7/1/3},
issn={2374-216X},
abstract={Leukocytosis, specifically granulocytosis in malignancy is a common finding with various etiologies. Graulocytosis associated with esophageal cancer has not commonly been reported in case reports in the United States. Furthermore, granulocyte colony stimulating factor (G-CSF) producing tumors have been associated with a variety of cancers. However, G-CSF producing esophageal tumors are rare. The diagnosis is established through serum G-CSF levels and immunohistochemistry staining of tumor cells. Here, we report a case of a 72-year-old woman with persistent granulocytosis leading to the diagnosis of esophageal squamous cell carcinoma (ESCC). Although, our case did not report serum G-CSF levels, we strongly suspect it to be the underlying etiology in our case. Additionally, through our missed opportunity, we hope to emphasize and increase awareness of G-CSF producing ESCC.},
doi={10.12691/ajmcr-7-1-3}
publisher={Science and Education Publishing}
}