eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2018-12-09 6 11 222 223 10.12691/ajmcr-6-11-1 AJMCR20186111 article Al Shabibi Buthina 1 Al Hashmi Samiya 2 Al Hashami Hilal hashamihs@gmail.com 3 Pediatrics Intern, Royal Hospital, Muscat, Oman Pediatrician, Royal Hospital, Muscat, Oman Pediatrics Infectious Diseases consultant, Royal Hospital, Muscat, Oman Salmonellae is one of determine infectious cause of acute gastroenteritis among children all over the world. It causes acute and self-limited gastroenteritis which can be complicated by Severe infection with central nervous system (CNS) involvement that can carry high risk of morbidity and mortality. Here, we report a case of Salmonella species acute gastroenteritis followed by severe sepsis with neurological manifestations in a child who is known case of Autosomal Recessive polycystic kidney with liver fibrosis. The infection was successfully treated with intravenous antibiotic along with short course of steroids. The child has complete recovery without any sequelae. In conclusion, this report demonstrates that use of steroid in severe salmonella infection with CNS involvement can improve the outcome. http://pubs.sciepub.com/ajmcr/6/11/1/ajmcr-6-11-1.pdf Salmonellae species sepsis steroids