eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2017-01-23 5 1 4 7 10.12691/ajmcr-5-1-2 AJMCR2017512 article Zhou Liang 1 Mingru Yin 1 Ai Ai 1 Yun Wang 1 Qiuju Chen 1 Songguo Xue 1 Yanping Kuang Kuangyanp@126.com 1 Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China This study reports an IVF patient who had adenomyosis underwent 2 in vitro fertilization (IVF) cycles and 3 frozen embryo transfer (FET) cycles but all failed. Then a Levonorgestrel-releasing intrauterine system (LNG-IUS) was inserted into her uterine. When her next menstrual period did not occur, the patient performed a urinary pregnancy test and it was positive. The pregnancy progressed normally and the delivery was uncomplicated. An elective Caesarean delivery was performed at 39 weeks gestation. The IUD was found in the placenta and the postpartum recovery was uneventful. This is the first report of a woman, who having been identified with uterine adenomyosis, delivered a normal female infant with an LNG-IUS in situ. This case report indicated that LNG-IUS may play some roles in changing the uterine environment of adenomyosis. http://pubs.sciepub.com/ajmcr/5/1/2/ajmcr-5-1-2.pdf Levonorgestrel-releasing intrauterine system in vitro fertilization adenomyosis