eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2016-05-30 4 5 175 179 10.12691/ajmcr-4-5-9 AJMCR2016459 article Eva Kovacs-Benke evakovacsbenke@hotmail.com 1 Cancer Immunology Research, 4127 Birsfelden, Switzerland Systemic lupus erythematosus (SLE) is a chronic, autoimmune, connective tissue disorder with multi-organ involvement. Reported here is the case of a 33-year-young women with a 12-year history of lupus erythematosus. The article documents the development of lupus: First phase/ preliminary phase (13-21 years of life); Second phase/acute cutaneous lupus erythematosus (22-27 years of life); Third phase/systemic lupus erythematosus (from 28 years of life). The parameters of serological test and blood test were measured regularly during the course of the disease. The MRI-investigation was carried out three times. The clinical symptoms are evaluated in relation to the laboratory parameters All these data with the therapeutic modalities and the trigger factor(s) are disclosed. http://pubs.sciepub.com/ajmcr/4/5/9/ajmcr-4-5-9.pdf autoimmune disease lupus erythematosus cutaneous systemic lupus erythematosus corticosteroids