eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2016-05-13 4 5 158 159 10.12691/ajmcr-4-5-3 AJMCR2016453 article Ines Kechaou kechaou.ines@topnet.tn 1 Eya Cherif 1 Imene Boukhris 1 Samira Azzabi 1 Chékib Kooli 1 Lamia Ben Hassine 1 Narjes Khalfallah 1 Internal Medicine Department, University hospital of Charles Nicolle, Tunis, Tunisia Pernicious anemia can cause several neurologic impairment. Ischemic stroke has been reported as a rare complication of pernicious anemia. We report a case of 51-year-old woman, who presented with ischemic stroke. Hyperhomocysteinemia due to pernicious anemia was diagnosed while looking for secondary causes of the cerebral event. She was treated with vitamin B12 that improved her anemia but not her neurological impairment. http://pubs.sciepub.com/ajmcr/4/5/3/ajmcr-4-5-3.pdf pernicious anemia stroke vitamine B12 homocysteine