Science and Education Publishing American Journal of Medical Case Reports 2374-216X 4 2 2016 2 27 Primary Signet-ring Cell Carcinoma of the Uterine Corpus: A Case Report and Review of the Literature 51 54 EN Shivali P. Marketkar Taslima Hossain W. Dwayne Lawrence M. Ruhul Quddus Department of Pathology, Women & Infants Hospital/Alpert Medical School of Brown University, Providence, RI 02905 AJMCR2016425 10.12691/ajmcr-4-2-5 2015 9 26 2015 12 27 2016 2 25 Pure signet-ring cell carcinomas of the uterine corpus usually raise the suspicion for a metastatic tumor from other primary sites, e.g., breast or the gastrointestinal tract. And if primary in the uterus, it is more commonly of uterine cervical origin with secondary involvement of the corpus. In general, pure mucinous carcinoma of the endometrium is rare and pure signet-ring cell carcinoma, a form of mucinous carcinoma, is even rarer. Only sparse case reports of primary mucinous adenocarcinoma of the uterine corpus with signet-ring cell features have been described in literature. We report here a case of pure mucinous signet-ring cell carcinoma of the uterine corpus in a 63 year-old morbidly obese woman.