@article{ajmcr2016413,
author={{valliyot, Balakrishnan and KK, Saroshkumar and SM, Sarin and B, Kadeeja beevi and alex, Nirmal mathew and thomas, Tency joshu},
title={A Rare Presentation of Medullary Carcinoma Thyroid},
journal={American Journal of Medical Case Reports},
volume={4},
number={1},
pages={8--11},
year={2016},
url={http://pubs.sciepub.com/ajmcr/4/1/3},
issn={2374-216X},
abstract={Medullary Thyroid Carcinoma (MTC) is a rare thyroid tumor that arises from neural crest-derived Calcitonin producing Para follicular C cells and accounts for approximately 4 % of thyroid malignancies. This neuroendocrine tumor typically is an aggressive cancer, with secretion of several neuro-humoral mediators. We report a case of 49 year old male patient who presented with episodes of chest discomfort and abdominal pain associated with loud screaming of unknown etiology, on evaluation found to have Medullary Thyroid Carcinoma as its cause. MTC usually present as palpable firm to hard thyroid nodules or enlargement of regional lymph nodes. Since the systemic symptoms of MTC are nonspecific, it is challenging to diagnose MTC when patients first presents with systemic symptoms as in our patient. This case is reported to highlight the unusual presentation of this rare thyroid tumor and to emphasize the need for meticulous clinical examination and high index of suspicion to diagnose it.},
doi={10.12691/ajmcr-4-1-3}
publisher={Science and Education Publishing}
}