eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2015-07-02 3 8 244 246 10.12691/ajmcr-3-8-6 AJMCR2015386 article Parijat Sen 1 Abhishek Kumar 2 Mary Mathews mary.mathews@live.ca 3 Daphne Macbruce 4 Richard Miller 4 Department of Internal Medicine, St. Michael's Medical Center, Newark, USA Department of Hematology and Oncology, St. Joseph's Regional Medical Center, New Jersey, USA Department of Internal Medicine, St. Joseph's Regional Medical Center, New Jersey, USA Department of Pulmonary Medicine, St. Michael's Medical Center, Newark, USA Multiple Myeloma usually presents with end organ damage like bone symptoms such as pain, pathologic fracture, renal dysfunction, chronic fatigue from anemia or symptoms of hypercalcemia. Although frequently associated with venous thromboembolisms, the presentation of multiple myeloma with pulmonary embolism as its initial manifestation is extremely rare. We report the case of a 60 y/o Hispanic male who presented with a Pulmonary Embolism, further diagnostic test revealed an underlying diagnosis of Multiple Myeloma. http://pubs.sciepub.com/ajmcr/3/8/6/ajmcr-3-8-6.pdf pulmonary embolism multiple myeloma initial manifestation