eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2015-05-15 3 6 158 159 10.12691/ajmcr-3-6-2 AJMCR2015362 article Severe Hemolysis as the First Manifestation of Acute Hepatitis A in an Adult with G6PD Deficiency and Positive ANA Dhrubajyoti Bandyopadhyay drdhrubajyoti87@gmail.com 1 Adrija Hajra 2 Sabyasachi Mukhopadhyay 3 Vijayan Ganesan 4 Manas layek 5 Debarati Bhar 5 Diptak Bhowmick 5 Cankatika choudhury 5 Partha Sarathi Karmakar 5 Department of accident and emergency, Lady Hardinge Medical College, New Delhi Department of Internal Medicine, IPGMER, Kolkata RG Kar medical college, Kolkata Department of Internal Medicine, RG Kar Medical College, Kolkata Lady hardinge medical college, New delhi We report a case of hemolytic anemia as an initial manifestation of hepatitis A virus infection. On admission, the patient had anemia, reticulocytosis, and direct and indirect hyperbilirubinemia. On subsequent examination, he had both glucose-6-phosphate dehydrogenase deficiency (G6PD) and autoimmune antibodies. http://pubs.sciepub.com/ajmcr/3/6/2/ajmcr-3-6-2.pdf Glucose-6-phosphate dehydrogenase deficiency (G6PD) Hepatitis A Antinuclear antibody (ANA)