Science and Education Publishing American Journal of Medical Case Reports 2374-216X 3 4 2015 04 12 Gilbert's Syndrome Successfully Treated with the Paleolithic Ketogenic Diet 117 120 EN Csaba Tóth Zsófia Clemens Paleomedicina Hungary Ltd., Evolutionary Medicine Working Group, Budapest, H-1026 Hidász u. 3/A, Hungary AJMCR2015349 10.12691/ajmcr-3-4-9 2015 03 17 2015 04 03 2015 04 12 Gilbert's syndrome (GS) is a common hyperbilirubinaemia syndrome caused by reduced conjugation of serum bilirubin by the liver. Although it is considered as a common and harmless condition not requiring treatment symptoms associated with GS may be unfavorable. Here we present a case of GS where high level of total and direct bilirubin, yellowish discoloration of the sclera as well as associated symptoms including migraine, fatigue and granulomatosus dermatitis were reversed following a shift toward the popular paleolithic and then toward the paleolithic ketogenic diet.