Science and Education Publishing American Journal of Medical Case Reports 2374-216X 3 4 2015 03 20 A Case of Acute Myeloid Leukemia with Bilateral Leukemic Optic Nerve Infiltration 111 112 EN Yıldırım Rahşan Urlu Selin Merih Sincan Gülden Atatürk University, School of Medicine, Departments of Haematology, Erzurum, TURKEY Kaban Göktürk Karaman Adem Bilen Yusuf AJMCR2015347 10.12691/ajmcr-3-4-7 2015 01 27 2015 03 10 2015 03 20 Ocular involvement in patients with leukemia may be due to various reasons and it is characterized by various clinical symptoms. Ocular problems in patients who have acute myeloid leukaemia (AML) are commonly observed. Orbital and ocular lesions carry a poor prognosis in patients with acute myeloid leukemia. Direct invasion of the retina and choroid with the neoplastic cells is common, but the involvement of the optic nerve, uveal tract are relatively rare. Ocular symptoms include blurred vision and diplopia due to the involvement of optic nerves. This paper reports a 68 year old patient with AML. 5 azasitidin was initiated for treatment. By the second cycle, he complained of vision loss for right eye. These findings occured for left eye after three days. Optic nerve involvement was found with orbital magnetic resonance imaging with contrast. We report these patient because of rarity.