eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2015-02-27 3 4 95 97 10.12691/ajmcr-3-4-2 AJMCR2015342 article Prahlad Neupane 1 Prasanna Dahal prince_prasanna@hotmail.com 2 Birat Acharya 3 Sagar raj pandey 4 Ramesh Gautam 5 Consultant Paediatrician (MD) Bijayapur Hospital, Dharan-10, Sunsari, Nepal Clinical Pharmacist (Msc, PharmD) Bijayapur Hospital, Dharan-10, Sunsari, Nepal Physician (MBBS) Bijayapur Hospital, Dharan-10, Sunsari, Nepal Consultant Pathologist (MD) Bijayapur Hospital, Dharan-10, Sunsari, Nepal lab technologist (BMLT), Bijayapur Hospital, Dharan-10, Sunsari, Nepal Although leukemia's are the most common malignant disease seen in children, it occurs rarely in neonates. Only few cases of congenital leukemia have been reported in literature. We report here a rare case of congenital lymphoblastic leukemia in a 10 days old full term male neonate of normal home delivery who presented in the hospital with complaints of fast breathing and fever of 1 day duration. Initial clinical manifestation was that of Multi organ dysfunction syndrome due to late onset neonatal sepsis but was found to have acute leukemia on subsequent investigations. http://pubs.sciepub.com/ajmcr/3/4/2/ajmcr-3-4-2.pdf Neonate Infants Acute lymphoblastic leukemia malignancy