Science and Education Publishing American Journal of Medical Case Reports 3 1 2015 01 05 Vascular Leiomyoma of the Nasal Cavity: An Unusual Tumor 10 12 EN Faten Hammedi Department of Pathology, Fattouma Bourguiba Hospital, Monastir, Tunisia Manel Njima Nouha Ben Abdeljelil Nawrez Kolsi Rim Hadhri Ahmed Zrig Leila Njim Adnène Moussa Abdelfateh Zakhama AJMCR2015314 10.12691/ajmcr-3-1-4 2014 12 08 2014 12 26 2015 01 05 Background: Angioleiomyoma of the nasal cavity is an extremely rare benign tumor. Since the first case reported by Poch-Viñals R. et al. in 1967, only 23 cases of angioleiomyoma of the nasal cavity have been published in English literature. Methodology/principal findings: We report a 42-year-old woman who presented with nasal obstruction and small volume epistaxis episodes. In the physical exam and under nasal endoscopy, we founded a red lesion that measured 1.5 cm. Clinically and in imagery the tumor resembled an inverted papilloma. Pathological study revealed an angioleiomyoma of the nasal cavity. Conclusion: Angioleiomyoma was an unusual tumor of the nasal cavity. It is more common in females. Treatment for these tumors is based on local resection, and there are no reports of recurrence after total excision.