eng Science and Education Publishing American Journal of Medical Case Reports 2014-09-11 2 9 181 183 10.12691/ajmcr-2-9-5 AJMCR2014295 article Chettri ST 1 Karki Smriti 2 Paudel D d_pakh @yahoo.com 2 Shah BP 2 Shah SP 2 Manandhar S 2 Jayaswal R 2 Department of Otorhinolaryngology, BPKIHS, Dharan, Nepal Department of Pathology, BPKIHS, Dharan, Nepal Isolated laryngeal leishmaniasis is a rare condition and we report a 46 years old patient who presented with progressive, non fluctuating hoarseness of voice for 8 months along with foreign body sensation of throat and difficulty in swallowing. Indirect laryngoscopy followed by flexible nasoendoscopy revealed grossly edematous epiglottis, right arytenoid, right aryepiglottic fold and medial wall of the right pyriform sinus. Direct laryngoscope was performed under general anesthesia and biopsy was taken. The histopathology report section revealed numerous extracellular L.D. bodies in an inflammatory milieu comprising of lymphocytes, neutrophils and macrophages set in an edematous subepithelial stroma. He has no other systemic manifestation. He had no HIV infection or immunocompromised condition nor took immunosuppressive drugs. He responded well with liposomal Amphotericin B. http://pubs.sciepub.com/ajmcr/2/9/5/ajmcr-2-9-5.pdf leishmania donovani LD Bodies larynx