Science and Education Publishing American Journal of Medical Case Reports 2 8 2014 08 28 A Case of Hypophosphatemic Rickets with the Secondary Hyperparathyroidism 158 160 EN Bar?? Sar?ak?al? Esma Jamaspishvili Department of Internal Medicine, Division of Endocrinology, Adana, Turkey Mehtap Evran Murat Sert Tamer Tetiker AJMCR2014284 10.12691/ajmcr-2-8-4 2014 08 09 2014 08 25 2014 08 28 Secondary hyperparathyroidism is an unusual complication of hypophosphatemic rickets during the treatment. As there is growing evidence that a high phosphate diet may induce secondary hyperparathyroidism and even tertiary hyperparathyroidism caused by hyperplasia of the parathyroid glands. Serum calcium, phosphate and also parathyroid hormone should be measured regularly to catch the early diagnosis of secondary hyperparathyroidism during the treatment of hypophosphatemic rickets patients, since this stage is reversible with the arrangement of calcitriol and phosphate. We report a case of secondary hyperparathyroidism due to hypophosphatemic rickets patient, under the treatment of regular calcitriol and oral phosphate related to her serum phosphate levels. She had been treated since her childhood ages for growth retardation and bone deformities. She had, subsequently developed significant hyperparathyroidism during follow up.