Science and Education Publishing American Journal of Medical Case Reports 2 4 2014 05 07 Atypical Presentation of Plasmacytoma 82 83 EN Bayram Berkta? Mehmet Ali Erkurt Ilhami Berber Ilknur Nizam Turgut Ozal Medical Center, Hematology Department Mustafa Koroglu Engin Selcuk Burak Yavuz Yagar Emin Kaya Irfan Kuku AJMCR2014243 10.12691/ajmcr-2-4-3 2014 03 29 2014 05 07 2014 05 07 Plasmacytoma is a tumor seen with multiple myeloma and its localized forms are solitary bone plasmacytoma and extramedullary plasmacytoma. While the most frequent locations are vertebrae, sternum, nasopharynx, paranasal sinuses, rarely mediastinum, kidney, testis and ovary may be involved. In this case, relapsed multiple myeloma with atypical extramedullary plasmacytoma located in the frontal region is presented.