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Greetings! I hope you are well.

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Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

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Carcinoma Breast Male: A Case Report

Sujit K Prasad, Anuj Kumar Srivastava*

Additional professor, Department of surgery, SSR Medical College, Mauritius

Abstract: Carcinoma of male breast is a rare cancer in male and accounts for less than 1% of all breast cancers. Affected men are usually in their 7th or 8th decade. In a study in India 0.7% of breast carcinoma is seen in men. Predisposing factors include genetic factors, exposure to radiation and excess estrogen. High exposure to estrogen may result from excess estrogen conditions or due to androgen deficiency states.

Keywords: carcinoma, male breast, estrogen excess states, mastectomy

Received November 20, 2013; Revised March 05, 2014; Accepted March 18, 2014

Citation: Sujit K Prasad, Anuj Kumar Srivastava, Carcinoma Breast Male: A Case Report. American Journal of Medical Case Reports, 2 (3). 48-49. January 2014. doi:10.12691/ajmcr-2-3-1

1. Introduction

The affected male with carcinoma breast is usually in his sixties of seventies. Histological types and routes of metastasis(lymphatics and vascular) of male breast cancer are similar as in females. Hence the TNM staging system of male breast carcinoma is same as in females. Excess estrogen exposure is a common cause and may result from excess estrogen levels or due to deficient states. Genetic mutation, obesity, alcoholism, liver disease, senescence are important predisposing factors. Men with BRCA1, BRCA2 and Klinefelter’s syndrome are at highest risk of developing breast cancer. Size of the tumour and lymph node status are prognostic determinants.

2. Case Report

Figure 1. Rightt breast shows retracted nipple and sub

A 65 year old male presented with “deformity of the right side of chest” On examination, the nipple retraction was apparent but there was no nipple discharge. A firm retroareolar mass of size 3 X 3 cm (approx.) was palpable. There were no clinically palpable axillary lymph nodes. The left breast and axilla were normal. FNAC of right breast lesion was done which depicted ductal epithelial carcinoma. Modified radical mastectomy with axillary clearance was done on priority. Patient is now on Tamoxifen which we intend to continue for 5 years.

Figure 2. Shows Modified Radical Mastectomy Dissec Areolar mass

Figure 3. Shows axillary clearance

Figure 4. Shows resected breast

3. Discussion

Male breast cancer has identical pathology as in females, but lesions infiltrate locally faster due to lesser breast tissue. In 50% of cases, lesion in male is in advanced stageIII. Hence the treatment guidelines are based on experience in female breast cancer management doing mastectomy initially followed by relevant adjuvant therapy.

References

[1]   | Schottenfeld D, Lilienfeld AM, Diamond H (1963); Some observations on epidemiology of breast cancer among males, American journal of public health 53, 890897.
[2]   | Donegan WL (1991) Cancer of breast in men, CA-A journal of clinicians 41, 339354.
[3]   | Sosco AJ, Lowenfel AB, Pasker de jong P (1993) Epidemiology of male breast cancer, International Journal of Cancer 53, 538549.
[4]   | Stromm HH,Olson J (1999) Risk of breast cancer in offspring of male breast cancer patient, Lancet 353, 209.
[5]   | Johansen Taber KA et al, Male breast cancer; Risk factors, diagnosis, management; Oncology Reports2010; 24; 1115.