eng Science and Education Publishing American Journal of Medical Case Reports 2014-11-04 2 11 247 249 10.12691/ajmcr-2-11-6 AJMCR20142116 article Yasir Bashir 1 Nusrat Bashir 2 Sajad Geelani 3 Asif Ahmed drasifahmed@gmail.com 4 Manzoor Parry 4 Shabeer Ahmad 5 Javid Rasool 5 Department of Critical care, Sheri-kashmir institute of medical sciences, soura, Srinagar j&k, India Department of laboratory hematology, Sheri-kashmir institute of medical sciences, soura, Srinagar, j&k, India Department of clinical hematology Sheri-kashmir institute of medical sciences, soura, Srinagar, j&k, India Department of pediatrics Sheri-kashmir institute of medical sciences, soura, Srinagar, j&k, India Department of general surgery Sheri-kashmir institute of medical sciences, soura, Srinagar, j&k, India Hyperphagia (also referred to as polyphagia) is a serious eating disorder defined as an extreme unsatisfied drive to consume food and the most common sign that aperson has hyperphagia is obesity. It can be caused commonly by variety of congenital obesity syndromes and rarely by acquired hypothalamic dysfunction.Here we report a clinical manifestation of a child who was a diagnosed case of acute lymphoblastic leukemia and was on maintenance chemotherapy when parents noted her overeating and on evaluation she proved to have central nervous system relapse. http://pubs.sciepub.com/ajmcr/2/11/6/ajmcr-2-11-6.pdf hyperphagia acute lymphoblastic leukemia relapse