@article{ajmcr20231128,
author={{Muramatsu, Ken-ichi and Takeuchi, Ikuto and Ota, Soichiro and Yanagawa, Youichi},
title={Transient Decrease of Insulin Secretion after COVID-19 Infection in a Patient with Hyperosmolar Hyperglycemic Syndrome},
journal={American Journal of Medical Case Reports},
volume={11},
number={2},
pages={37--40},
year={2023},
url={http://pubs.sciepub.com/ajmcr/11/2/8},
issn={2374-216X},
abstract={A 52-year-old male was transported to a local medical facility due to unconsciousness and involuntary movement. His past history included only hypertension. He consumed over 2 L of soft drink per day. His body mass index was 34. As he had hyperosmolar hyperglycemic syndrome and COVID-19 infection, he was transferred to our department. On arrival, he was in a coma and pre-shock state. He was therefore intubated. Initially, his blood C-peptide level was low, and he showed hyperglycemia with ketosis. Whole body computed tomography (CT) showed pneumonia. He was diagnosed with hyperosmolar hyperglycemic syndrome with ketosis, COVID-19 infection, convulsion, hemoconcentration, liver dysfunction, rhabdomyolysis, pancreatitis, renal failure and hypernatremia. He was admitted to the intensive care unit, where he was successfully treated. His blood C-peptide returned to the normal range (2.2 ng/mL) on day 20, and he returned to the local medical facility on day 21. This is the first report of transient decrease in insulin secretion after COVID-19 infection in a patient with a combination hyperosmolar hyperglycemic syndrome and ketosis. Further prospective studies are needed to clarify the characteristics of the insulin secretion function following COVID-19 infection.},
doi={10.12691/ajmcr-11-2-8}
publisher={Science and Education Publishing}
}