eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2023-11-07 11 11 167 168 10.12691/ajmcr-11-11-1 AJMCR202311111 article Adrian M. Alonso 1 Matilda L. Culp 1 University of Florida, Department of Internal Medicine1, Gainesville, FL Anti-SAE1 antibody is a rarely reported, myositis-specific antibody, which is most clinically associated with affecting the gastrointestinal tract, skin, and lungs. This case demonstrates a patient presenting to the hospital with signs of dermatomyositis, later found to be anti-SAE1 positive. He was promptly treated with immunosuppressive medications, including IVIG, a novel therapeutic agent for dermatomyositis. This case further elucidates the importance of identifying anti-SAE1-positive patients in dermatomyositis. http://pubs.sciepub.com/ajmcr/11/11/1/ajmcr-11-11-1.pdf dermatomyositis anti-SAE1 polymyositis antibody immunology