eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2022-08-09 10 8 197 198 10.12691/ajmcr-10-8-5 AJMCR20221085 article Ilse Novis 1 Hailey Novis, Ingie Sorour, Khaled Sorour ksorour@signature-healthcare.org 1 Department of Anesthesia, Critical Care, and Pain Management; Signature Brockton Hospital; Brockton, MA A patient receiving Norepinephrine infusion through a peripheral IV experienced vasopressor extravasation. Due to an unavailability of phentolamine in the hospital, it was decided to attempt a new method of extravasation treatment through intraarterial injection of nitroprusside, restoring blood flow to the affected area. To mitigate the recurrence of vasospasms given the short half-life of nitroprusside, ropivacaine was injected. This regime successfully alleviated the extravasation-induced vasospasm and the patient recovered full function. http://pubs.sciepub.com/ajmcr/10/8/5/ajmcr-10-8-5.pdf extravasation norepinephrine nitroprusside ropivacaine vasopressor complication