eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2022-03-20 10 3 72 76 10.12691/ajmcr-10-3-8 AJMCR20221038 article Patient with Systemic Lupus Erythematosus who Presented with Area Postrema Syndrome after COVID-19 Vaccination Carlos Romero-G¨®mez carlosrg1968@gmail.com 1 Pablo L¨®pez-Quirantes 1 Jos¨¦ Antonio Reyes-Bueno 2 Ricardo G¨®mez-Huelgas 2 Medicina Interna, Hospital Regional Universitario, M¨¢laga, Spain Neurolog¨ªa, Hospital Regional Universitario, M¨¢laga, Spain Area postrema syndrome is a disorder that is included within the neuromyelitis optica spectrum (NMOSD), a group of severe inflammatory disorders of the central nervous system that primarily affect the optic nerve and spinal cord. The cause of NMOSD is unknown, but it has been linked to infections, vaccines and associated with autoimmune diseases. We present the case of a patient with a history of systemic lupus erythematosus who presented with area postrema syndrome after vaccination with COVID-19. http://pubs.sciepub.com/ajmcr/10/3/8/ajmcr-10-3-8.pdf postrema area syndrome neuromyelitis optica systemic lupus erythematosus covid-19 vaccination